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Thiethylperazine dimaleate

🥰Excellent
Catalog No. T17072Cas No. 1179-69-7
Alias Toresten, Thiethylperazine maleate, Norzine

Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.

Thiethylperazine dimaleate

Thiethylperazine dimaleate

🥰Excellent
Purity: 99.07%
Catalog No. T17072Alias Toresten, Thiethylperazine maleate, NorzineCas No. 1179-69-7
Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.
Pack SizePriceAvailabilityQuantity
5 mg$48In Stock
10 mg$73In Stock
25 mg$133In Stock
50 mg$223In Stock
100 mg$343In Stock
500 mgInquiryIn Stock
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Purity:99.07%
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Product Introduction

Bioactivity
Description
Thiethylperazine dimaleate (Thiethylperazine maleate) is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.
In vitro
Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects[2].
In vivo
In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels[2].
AliasToresten, Thiethylperazine maleate, Norzine
Chemical Properties
Molecular Weight631.76
FormulaC30H37N3O8S2
Cas No.1179-69-7
SmilesOC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCSc1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1
Relative Density.1.24g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (79.14 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5829 mL7.9144 mL15.8288 mL79.1440 mL
5 mM0.3166 mL1.5829 mL3.1658 mL15.8288 mL
10 mM0.1583 mL0.7914 mL1.5829 mL7.9144 mL
20 mM0.0791 mL0.3957 mL0.7914 mL3.9572 mL
50 mM0.0317 mL0.1583 mL0.3166 mL1.5829 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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