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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | In Stock | |
10 mg | $47 | In Stock | |
25 mg | $89 | In Stock | |
50 mg | $126 | In Stock | |
100 mg | $163 | In Stock | |
1 mL x 10 mM (in DMSO) | $34 | In Stock |
Description | Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase . |
In vitro | Tyrphostin A1 inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.tyrphostin A1 blocks CD40L-induced translocation of NF-kappaB to the nucleus, and reduces the activation of IL-12 p40 gene.?In vivo therapy with A1 leads to decrease in generation of myelin basic protein (MBP) specific encephalitogenic T cells[1]. |
Alias | AG9, Tyrphostin 1 |
Molecular Weight | 184.19 |
Formula | C11H8N2O |
Cas No. | 2826-26-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (542.92 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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