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UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $43 | In Stock | |
50 mg | $68 | In Stock | |
100 mg | $107 | In Stock | |
200 mg | $161 | In Stock |
Description | UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively. |
Targets&IC50 | HDAC8:1.5 μM, HDAC3:0.06 μM, HDAC1:0.5 μM, HDAC2:0.1 μM |
In vivo | The combination of paritaprevir, ritonavir, ombitasvir (an NS5A protein inhibitor), and dasabuvir (an NS5B non-nucleoside polymerase inhibitor) with or without RBV has been approved to treat HCV genotype 1 infections1[1]. |
Molecular Weight | 271.15 |
Formula | C11H15BrN2O |
Cas No. | 537672-41-6 |
Smiles | CCCCNNC(=O)c1ccc(Br)cc1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 75 mg/mL (276.6 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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