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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $147 | In Stock | |
5 mg | $369 | In Stock | |
10 mg | $556 | In Stock | |
25 mg | $896 | In Stock | |
50 mg | $1,220 | In Stock | |
100 mg | $1,650 | In Stock | |
500 mg | $3,290 | In Stock | |
1 mL x 10 mM (in DMSO) | $397 | In Stock |
Description | VT107 is a potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer[1]. |
In vitro | VT107 (3 μmol/L; 20 h; HEK293T cells) effectively hinders the palmitoylation of endogenous TEAD1 and TEAD3 proteins, as well as effectively obstructs the palmitoylation of endogenous TEAD4 protein. Moreover, VT107 demonstrates potent inhibition of the proliferation of NF2 mutant/deficient cell lines.[1] |
In vivo | VT107 (10 mg/kg; p.o.; mouse) is 55% available. Intravenous Injection half-live is 2.7 h.[1] |
Molecular Weight | 435.44 |
Formula | C25H20F3N3O |
Cas No. | 2417718-63-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (114.83 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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