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WM-8014

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Catalog No. T4362Cas No. 2055397-18-5
Alias MOZ-IN-3

WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.

WM-8014

WM-8014

🥰Excellent
Purity: 99.95%
Catalog No. T4362Alias MOZ-IN-3Cas No. 2055397-18-5
WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
2 mg$75In Stock
5 mg$117In Stock
10 mg$178In Stock
25 mg$352In Stock
50 mg$523In Stock
100 mg$757In Stock
1 mL x 10 mM (in DMSO)$138In Stock
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Purity:99.95%
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Product Introduction

Bioactivity
Description
WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.
Targets&IC50
MOZ:55 nM
In vitro
MOZ-IN-3is an inhibitor of MOZ(IC50=55 nM). MOZ-IN-3 causes cell senescence(IC50=1.6 μM) and suppresses the proliferation(IC50=551 nM).
Kinase Assay
Reactions are set up with Acetyl coenzyme A (AcCoA)(0.4 μM), N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin)(50 nM), MOZ enzyme(10 nM), and an acetyl-lysine specific antibody (final dilution 1: 10000).
AliasMOZ-IN-3
Chemical Properties
Molecular Weight384.42
FormulaC20H17FN2O3S
Cas No.2055397-18-5
SmilesCc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccc1
Relative Density.1.307 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (117.06 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6013 mL13.0066 mL26.0132 mL130.0661 mL
5 mM0.5203 mL2.6013 mL5.2026 mL26.0132 mL
10 mM0.2601 mL1.3007 mL2.6013 mL13.0066 mL
20 mM0.1301 mL0.6503 mL1.3007 mL6.5033 mL
50 mM0.0520 mL0.2601 mL0.5203 mL2.6013 mL
100 mM0.0260 mL0.1301 mL0.2601 mL1.3007 mL

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