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Wnt/β-catenin agonist 4

🥰Excellent
Catalog No. T60803Cas No. 912784-79-3

Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.

Wnt/β-catenin agonist 4

Wnt/β-catenin agonist 4

🥰Excellent
Purity: 99.61%
Catalog No. T60803Cas No. 912784-79-3
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
Pack SizePriceAvailabilityQuantity
5 mg$64In Stock
10 mg$105In Stock
25 mg$192In Stock
50 mg$328In Stock
100 mg$538In Stock
500 mg$1,150In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Purity:99.61%
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Product Introduction

Bioactivity
Description
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
In vitro
Wnt/β-catenin agonist 4, identified also as Derivative 83, demonstrates significant biological activity by enhancing ALP (alkaline phosphatase) activity by 2848% during the differentiation of the ST2 cell line into osteoblasts at a concentration of 11 μM over 4 days. Additionally, at a concentration of 120 μM for 24 hours, it exhibits a 1049% increase in β-catenin activity in HEK293 and SW480 cells. [1]
Chemical Properties
Molecular Weight314.31
FormulaC16H15FN4O2
Cas No.912784-79-3
SmilesFc1ccc(cc1)-c1cc(no1)C(=O)NCCCn1ccnc1
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (357.9 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1816 mL15.9079 mL31.8157 mL159.0786 mL
5 mM0.6363 mL3.1816 mL6.3631 mL31.8157 mL
10 mM0.3182 mL1.5908 mL3.1816 mL15.9079 mL
20 mM0.1591 mL0.7954 mL1.5908 mL7.9539 mL
50 mM0.0636 mL0.3182 mL0.6363 mL3.1816 mL
100 mM0.0318 mL0.1591 mL0.3182 mL1.5908 mL

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