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Yohimbine hydrochloride

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Catalog No. T2142Cas No. 65-19-0
Alias Yohimbine HCl, Antagonil

Yohimbine hydrochloride (Antagonil) is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.

Yohimbine hydrochloride

Yohimbine hydrochloride

🥰Excellent
Purity: 100.00%
Catalog No. T2142Alias Yohimbine HCl, AntagonilCas No. 65-19-0
Yohimbine hydrochloride (Antagonil) is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
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Purity:100.00%
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Product Introduction

Bioactivity
Description
Yohimbine hydrochloride (Antagonil) is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
In vivo
LD50: 55 mg/kg,i.p.,mice
AliasYohimbine HCl, Antagonil
Chemical Properties
Molecular Weight390.9
FormulaC21H27ClN2O3
Cas No.65-19-0
SmilesCOC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 42.5 mg/mL (108.72 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5582 mL12.7910 mL25.5820 mL127.9100 mL
5 mM0.5116 mL2.5582 mL5.1164 mL25.5820 mL
10 mM0.2558 mL1.2791 mL2.5582 mL12.7910 mL
20 mM0.1279 mL0.6395 mL1.2791 mL6.3955 mL
50 mM0.0512 mL0.2558 mL0.5116 mL2.5582 mL
100 mM0.0256 mL0.1279 mL0.2558 mL1.2791 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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