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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $133 | In Stock | |
5 mg | $320 | In Stock | |
10 mg | $470 | In Stock | |
25 mg | $772 | In Stock | |
50 mg | $1,080 | In Stock | |
100 mg | $1,460 | In Stock | |
500 mg | $2,920 | In Stock |
Description | ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolated airways in guinea pigs.ZD-2138 can be used for the treatment of asthma disease. |
In vitro | The 5-lipoxygenase inhibitor ZD-2138 (1 μM) significantly inhibited these neurally mediated tachykinergic contractions, by approximately 50%, yet had no effect on the contractions evoked by stimulating tachykinergic fibers in an action potential-independent fashion with capsaicin or by exogenously applied neurokinin A.[1] |
Alias | Ici-D2138 |
Molecular Weight | 397.44 |
Formula | C23H24FNO4 |
Cas No. | 140841-32-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (37.74 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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