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3-demethylcolchicine

3-demethylcolchicine
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Purity:99.41%
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3-demethylcolchicine

Catalog No. TN6706Cas No. 7336-33-6
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$47In Stock
5 mg$74In Stock
10 mg$117In Stock
25 mg$231In Stock
50 mg$359In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Related Compound Libraries of "3-demethylcolchicine"

Product Introduction

Bioactivity
Description
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.
In vitro
3-demethylcolchicine showed an appreciable effect in vitro and in vivo, in the lymphocytic leukemia P388 screen in mice, for their toxicity in mice, and for their binding to microtubule protein.
Chemical Properties
Molecular Weight385.41
FormulaC21H23NO6
Cas No.7336-33-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 10 mg/mL (25.95 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5946 mL12.9732 mL25.9464 mL129.7320 mL
5 mM0.5189 mL2.5946 mL5.1893 mL25.9464 mL
10 mM0.2595 mL1.2973 mL2.5946 mL12.9732 mL
20 mM0.1297 mL0.6487 mL1.2973 mL6.4866 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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