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8-OH-Dpat

8-OH-Dpat
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Catalog No. T4305Cas No. 78950-78-4
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8-OH-Dpat

Catalog No. T4305Alias 8-Hydroxy-DPATCas No. 78950-78-4

8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$55In Stock
25 mg$113In Stock
50 mg$178In Stock
100 mg$271In Stock
1 mL x 10 mM (in DMSO)$48In Stock
Bulk & Custom
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Product Introduction

Bioactivity
Description
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Targets&IC50
5-HT1A:pIC50 = 8.19, 5-HT7:
Alias8-Hydroxy-DPAT
Chemical Properties
Molecular Weight247.38
FormulaC16H25NO
Cas No.78950-78-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 49 mg/mL (198.07 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0424 mL20.2118 mL40.4236 mL202.1182 mL
5 mM0.8085 mL4.0424 mL8.0847 mL40.4236 mL
10 mM0.4042 mL2.0212 mL4.0424 mL20.2118 mL
20 mM0.2021 mL1.0106 mL2.0212 mL10.1059 mL
50 mM0.0808 mL0.4042 mL0.8085 mL4.0424 mL
100 mM0.0404 mL0.2021 mL0.4042 mL2.0212 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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