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8-OH-Dpat

Catalog No. T4305Cas No. 78950-78-4
Alias 8-Hydroxy-DPAT

8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.

8-OH-Dpat

8-OH-Dpat

Catalog No. T4305Alias 8-Hydroxy-DPATCas No. 78950-78-4
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$55In Stock
25 mg$113In Stock
50 mg$178In Stock
100 mg$271In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Product Introduction

Bioactivity
Description
8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Targets&IC50
5-HT1A:pIC50 = 8.19, 5-HT7:
Alias8-Hydroxy-DPAT
Chemical Properties
Molecular Weight247.38
FormulaC16H25NO
Cas No.78950-78-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 49 mg/mL (198.07 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0424 mL20.2118 mL40.4236 mL202.1182 mL
5 mM0.8085 mL4.0424 mL8.0847 mL40.4236 mL
10 mM0.4042 mL2.0212 mL4.0424 mL20.2118 mL
20 mM0.2021 mL1.0106 mL2.0212 mL10.1059 mL
50 mM0.0808 mL0.4042 mL0.8085 mL4.0424 mL
100 mM0.0404 mL0.2021 mL0.4042 mL2.0212 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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