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FSEN1
🥰Excellent
Catalog No. T77765Cas No. 862808-01-3
Alias 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces ferroptosis in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer.
FSEN1
🥰Excellent
Purity: 98.56%
Catalog No. T77765Alias 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazoleCas No. 862808-01-3
FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces ferroptosis in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $44 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $163 | In Stock | |
| 25 mg | $328 | In Stock | |
| 50 mg | $529 | In Stock | |
| 100 mg | $818 | In Stock |
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Purity:98.56%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces ferroptosis in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer. |
| In vitro | FSEN1 (0-15 µM; H460C Cas9 cells) exhibits a synthetic lethality effect with GPX4 inhibitors and sensitizes cancer cells to ferroptosis by inhibiting FSP1[1]. |
| Alias | 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Molecular Weight | 484.41 |
| Formula | C22H22BrN5OS |
| Cas No. | 862808-01-3 |
| Smiles | COC1=CC=C(C=C1)N1CCN(CC2=CN3C(S2)=NN=C3C2=CC=C(Br)C=C2)CC1 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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