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AA26-9

Catalog No. T3990 CAS 1312782-34-5

AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.

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AA26-9, CAS 1312782-34-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 31.00
2 mg	In stock	$ 44.00
5 mg	In stock	$ 72.00
10 mg	In stock	$ 122.00
25 mg	In stock	$ 222.00
50 mg	In stock	$ 369.00
100 mg	In stock	$ 549.00
1 mL * 10 mM (in DMSO)	In stock	$ 79.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
In vitro	AA26-9 inhibits enzymes originated from diverse functional subclasses of serine hydrolases, including peptidases (APEH, CTSA, PRCP), thioesterases (LYPLA1/2), lipases/phospholipases (AADACL1, ESD, ABHD6, PAFAH2, FAAH, LYPLA3), and uncharacterized enzymes (ABHD11, ABHD13, BAT5). AA26-9 inhibits 1/3 of the over 40 serine hydrolase found in T-cells.
Cell Research	AA26-9 is prepared in DMSO. Cells are cultured with 20 μM inhibitor AA26-9 or DMSO as a control for 4 h, lysed, separated into soluble and analyzed by competitive gel-based ABPP[1].

Molecular Weight	166.18
Formula	C7H10N4O
CAS No.	1312782-34-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (330.96 mM)

References and Literature

1. Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7(7):469-78.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Covalent Inhibitor Library Bioactive Compounds Library Max Lipid Metabolism Compound Library Anti-Obesity Compound Library Bioactive Compound Library Metabolism Compound Library Protease Inhibitor Library NO PAINS Compound Library

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Related compounds with same targets

AACOCF3 5α-Hydroxycostic acid Varespladib methyl Lp-PLA2-IN-15 Carbazochrome Lansoprazole LEI110 VU0155069

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AA26-9 1312782-34-5 Metabolism Proteases/Proteasome Serine Protease Phospholipase peptidases thioesterases AA269 serine esterases AA-26-9 AA26 9 Inhibitor lipases amidases inhibit cell inhibitor

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