Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 80.00 | |
5 mg | In stock | $ 172.00 | |
10 mg | In stock | $ 272.00 | |
25 mg | In stock | $ 547.00 | |
50 mg | In stock | $ 789.00 | |
100 mg | In stock | $ 1,080.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 189.00 |
Description | AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells). |
In vitro | AB-423 shows an inhibitory effect on relaxed circular DNA production in AML12-HBV10 and HepDE19 cells (EC50s: ~0.260 μM). AB-423 also suppresses cccDNA formation-dependent HBeAg production in the HepBHAe82 assay (EC50: 0.267 μM) and inhibits HBV DNA levels in culture supernatants of HepG 2.2.15 cells (EC50: 0.134 μM). |
Molecular Weight | 386.39 |
Formula | C17H17F3N2O3S |
CAS No. | 1572510-80-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (207.05 mM), Sonification and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AB-423 1572510-80-5 Microbiology/Virology HBV inhibit AB423 Hepatitis B virus AB 423 Inhibitor inhibitor