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AT-130

🥰Excellent
Catalog No. T26674Cas No. 211364-06-6
Alias AT 130

AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.

AT-130

AT-130

🥰Excellent
Purity: 98.62%
Catalog No. T26674Alias AT 130Cas No. 211364-06-6
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
Pack SizePriceAvailabilityQuantity
1 mg$35In Stock
5 mg$83In Stock
10 mg$133In Stock
25 mg$238In Stock
50 mg$356In Stock
100 mg$535In Stock
200 mg$735In Stock
1 mL x 10 mM (in DMSO)$89In Stock
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Purity:98.62%
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Product Introduction

Bioactivity
Description
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.
Targets&IC50
HBV:0.13 μM
AliasAT 130
Chemical Properties
Molecular Weight488.33
FormulaC22H22BrN3O5
Cas No.211364-06-6
SmilesCOc1ccccc1\C(Br)=C(/NC(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)N1CCCCC1
Relative Density.1.459 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 23 mg/mL (47.09 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0478 mL10.2390 mL20.4780 mL102.3898 mL
5 mM0.4096 mL2.0478 mL4.0956 mL20.4780 mL
10 mM0.2048 mL1.0239 mL2.0478 mL10.2390 mL
20 mM0.1024 mL0.5119 mL1.0239 mL5.1195 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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