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Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $31 | In Stock | |
25 mg | $61 | In Stock | |
50 mg | $95 | In Stock | |
100 mg | $173 | In Stock | |
200 mg | $253 | In Stock | |
1 mL x 10 mM (in DMSO) | $30 | In Stock |
Description | Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response. |
In vitro | Azoramide, a dual-function endoplasmic reticulum (ER) modulator, improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. |
In vivo | In two independent mouse models of obesity, Azoramide exhibits potent antidiabetic efficacy by improving insulin sensitivity and pancreatic β cell function. |
Molecular Weight | 308.83 |
Formula | C15H17ClN2OS |
Cas No. | 932986-18-0 |
Smiles | CCCC(=O)NCCc1csc(n1)-c1ccc(Cl)cc1 |
Relative Density. | 1.215 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (161.91 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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