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BI-6C9

Catalog No. T5827 CAS 791835-21-7

BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.

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BI-6C9, CAS 791835-21-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 60.00
2 mg	In stock	$ 88.00
5 mg	In stock	$ 147.00
10 mg	In stock	$ 247.00
25 mg	In stock	$ 458.00
50 mg	In stock	$ 678.00
100 mg	In stock	$ 966.00
1 mL * 10 mM (in DMSO)	In stock	$ 153.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.
Targets&IC50	TBid:20 µM(kd)

Molecular Weight	471.59
Formula	C23H25N3O4S2
CAS No.	791835-21-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 240 mg/mL (508.9 mM), Sonication is recommended.

References and Literature

1. Grohm J , Plesnila N , Culmsee C . Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death[J]. Brain, Behavior, and Immunity, 2010, 24(5):0-838.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Highly Selective Inhibitor Library Metabolism Compound Library Anti-Aging Compound Library Apoptosis Compound Library PPI Inhibitor Library Anti-COVID-19 Compound Library Bioactive Compounds Library Max Cuproptosis Compound Library Mitochondria-Targeted Compound Library

Related Products

Related compounds with same targets

L-685458 Oxcarbazepine Geranyl acetate Ruxolitinib Catechin Spautin-1 BI 2536 Nebularine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BI-6C9 791835-21-7 Apoptosis Metabolism Others Mitochondrial Metabolism Inhibitor fission Neurodegeneration Bid BI6C9 BI 6C9 Mitochodondrial death Mitochondria inhibit Glutamate stress Neuronal Bcl-2 Mitochondrial potential cell Oxidative membrane BI-6C-9 inhibitor

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