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Chlorogenic Acid

Catalog No. T2805 CAS 327-97-9

Synonyms: NSC-407296, 3-O-Caffeoylquinic acid, Heriguard

Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.

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Chlorogenic Acid, CAS 327-97-9

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 55.00

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Purity: 99.67%

Purity: 99.43%

Purity: 99.27%

Purity: 98.76%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
Source	Natural Products > Eucommiaceae > Eucommia

Synonyms	NSC-407296, 3-O-Caffeoylquinic acid, Heriguard
Molecular Weight	354.31
Formula	C16H18O9
CAS No.	327-97-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 66 mg/mL (186.3 mM)

DMSO: 66 mg/mL (186.3 mM)

H2O: 10mg/ml

References and Literature

1. Illing EA, et al. Otolaryngol Head Neck Surg. 2015 Aug;153(2):291-7. 2. Jang S A, Hwang Y H, Kim T, et al. Anti-Osteoporotic and Anti-Adipogenic Effects of the Water Extract of Drynaria roosii Nakaike in Ovariectomized Mice Fed a High-Fat Diet[J]. Molecules. 2019, 24(17): 3051. 3. Shim K S, Hwang Y H, Jang S A, et al. . Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice[J]. Nutrients. 2020, 12(7): 1927.

Citations

1. Jang S A, Hwang Y H, Yang H, et al. Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis. Biomedicine & Pharmacotherapy. 2022, 147: 112640. 2. Jang S A, Hwang Y H, Yang H, et al. Water Extract of Mentha arvensis L. Attenuates Estrogen Deficiency-Induced Bone Loss by Inhibiting Osteoclast Differentiation. Frontiers in Pharmacology. 2021, 12. 3. Shim K S, Hwang Y H, Jang S A, et al. Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice. Nutrients. 2020, 12(7): 1927 4. Jiang H, Chen J, Li X, et al. Systematic Identification of Chemical Components in Fufang Shuanghua Oral Liquid and Screening of Potential Active Components Against SA¸ n Protease. Journal of Pharmaceutical and Biomedical Analysis. 2022: 115118. 5. Jang S A, Hwang Y H, Kim T, et al. Anti-Osteoporotic and Anti-Adipogenic Effects of the Water Extract of Drynaria roosii Nakaike in Ovariectomized Mice Fed a High-Fat Diet. Molecules. 2019, 24(17): 3051 6. Jung M A, Song H K, Jo K, et al.Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.Biomedicine & Pharmacotherapy.2023, 161: 114482. 7. Jiang H, Chen J, Li X, et al.Systematic identification of chemical components in Fufang Shuanghua oral liquid and screening of potential active components against SARS-CoV-2 protease.Journal of Pharmaceutical and Biomedical Analysis.2023, 223: 115118. 8. Lee S J, Yang H, Kim S C, et al.Ethanol Extract of Radix Asteris Suppresses Osteoclast Differentiation and Alleviates Osteoporosis.International Journal of Molecular Sciences.2023, 24(22): 16526.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Anti-Cancer Clinical Compound Library Miao medicine Compound Library Anti-Cancer Drug Library Tobacco Monomer Library Anti-Cancer Active Compound Library Drug Repurposing Compound Library Microbial Natural Product Library Inhibitor Library Anti-Ovarian Cancer Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Chlorogenic Acid 327-97-9 Chromatin/Epigenetic Immunology/Inflammation Metabolism Microbiology/Virology NF-Κb Others Influenza Virus Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Antibacterial HIF-PH NSC-407296 NSC 407296 3-O-Caffeoylquinic acid Hypoxia-inducible factors Inhibitor Heriguard NSC407296 HIFs inhibit Bacterial inhibitor

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