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Coenzyme Q9

Catalog No. T5573 CAS 303-97-9

Synonyms: Ubiquinone Q9, Ubiquinone 9, CoQ9

Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.

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Coenzyme Q9, CAS 303-97-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 52.00
5 mg	In stock	$ 128.00
10 mg	In stock	$ 190.00
25 mg	In stock	$ 283.00
50 mg	In stock	$ 418.00
100 mg	In stock	$ 623.00
1 mL * 2.5 mM (in DMSO)	In stock	$ 196.00

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Purity: 99.47%

Purity: 99.32%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.
In vitro	Coenzyme Q9 were cardioprotective, as evidenced by their abilities to improve left ventricular performance and to reduce myocardial infarct size and cardiomyocyte apoptosis[1].
In vivo	Mutations in the gene that encodes Coenzyme Q9(CoQ9) are associated with encephalomyopathy and autosomal-recessive, neonatal-onset, primary CoQ10 deficiency.While in humans CoQ10 predominates, mice and C. elegans primarily rely on CoQ9 for electron transport through the mitochondrial respiratory chain and for antioxidant functions[2,3].
Animal Research	Guinea pigs were randomly divided into three groups: groups I and II were fed CoQ 9 and CoQ10, respectively, for 30 days while group III served as control.?After 30 days, the guinea pigs were sacrificed and isolated hearts were perfused via working mode were subjected to 30 min ischemia followed by 2 h of reperfusion.?Cardioprotection was assessed by evaluating left ventricular function, ventricular arrhythmias, myocardial infarct size, and cardiomyocyte apoptosis.?Samples of hearts were examined for the presence of CoQ9 and CoQ10[1].

Synonyms	Ubiquinone Q9, Ubiquinone 9, CoQ9
Molecular Weight	795.23
Formula	C54H82O4
CAS No.	303-97-9

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.5 mM

References and Literature

1. Lekli I, et al. Coenzyme Q9 provides cardioprotection after converting into coenzyme Q10. J Agric Food Chem. 2008 Jul 9;56(13):5331-7. 2. Duncan, A.J., Bitner-Glindzicz, M., Meunier, B., et al. A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: A potentially treatable form of mitochondrial disease.American Journal of Human Genetics 84(5), 558-566 (2009). 3. Lapointe, J., Wang, Y., Bigras, E., et al. The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice. Journal of Cell Biology 199(2), 215-224 (2012).

Related compound libraries

This product is contained In the following compound libraries：

Human Endogenous Metabolite Library Cuproptosis Compound Library Human Metabolite Library Gut Microbial Metabolite Library Natural Product Library for HTS Covalent Inhibitor Library Bioactive Compound Library Natural Product Library Antioxidant Compound Library Oxidation-Reduction Compound Library

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Keywords

Coenzyme Q9 303-97-9 Apoptosis Metabolism Endogenous Metabolite rodents Coenzyme Q-9 antioxidant chain transport left Ubiquinone Q9 Ubiquinone 9 Inhibitor Ubiquinone9 Coenzyme Q 9 ventricular Ubiquinone Q-9 CoQ 9 amphipathic CoQ9 electron inhibit Ubiquinone Q 9 endogenous CoQ-9 Ubiquinone-9 inhibitor

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