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Curculigoside

Catalog No. T6S1966 CAS 85643-19-2

Synonyms: Curculigoside, Janus kinase, Curculigoside A, NF-κB, JAK, Nuclear factor-κB, Nuclear factor-kappaB, STAT, inhibit, Inhibitor

1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidative injury induced by H2O2, suggesting that this compound may constitute a promising intervention against cardiovascular disorders.

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Curculigoside, CAS 85643-19-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Curculigoside, Janus kinase, Curculigoside A, NF-κB, JAK, Nuclear factor-κB, Nuclear factor-kappaB, STAT, inhibit, Inhibitor
Molecular Weight	466.439
Formula	C22H26O11
CAS No.	85643-19-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 84 mg/mL(180.1 mM)

Ethanol: 84 mg/mL(180.1 mM)

Pyridine, Methanol, etc.: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Liu M , Li Y , Yang S T . Curculigoside Improves Osteogenesis of Human Amniotic Fluid-Derived Stem Cells[J]. Stem Cells and Development, 2014, 23(2):146-154.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library HIF-1 Signaling Pathway Compound Library Traditional Chinese Medicine Monomer Library Natural Product Library for HTS Anti-Tumor Natural Product Library Oxidation-Reduction Compound Library Immunology/Inflammation Compound Library Kinase Inhibitor Library Stem Cell Differentiation Compound Library NF-κB Signaling Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.