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DDD85646

Catalog No. T27135Cas No. 1215010-55-1
Alias DDD-85646, DDD 85646

DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.

DDD85646

DDD85646

Purity: 99.76%
Catalog No. T27135Alias DDD-85646, DDD 85646Cas No. 1215010-55-1
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$316In Stock
10 mg$491In Stock
25 mg$717In Stock
50 mg$996In Stock
100 mg$1,370In Stock
1 mL x 10 mM (in DMSO)$347In Stock
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Purity:99.76%
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Product Introduction

Bioactivity
Description
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
Targets&IC50
NMT:1.44 nM(Ki, T. brucei), NMT:2 nM(EC50, T. brucei), NMT:2 nM(T. brucei), NMT:4 nM(human)
AliasDDD-85646, DDD 85646
Chemical Properties
Molecular Weight495.43
FormulaC21H24Cl2N6O2S
Cas No.1215010-55-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 95 mg/mL (191.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0184 mL10.0922 mL20.1845 mL100.9224 mL
5 mM0.4037 mL2.0184 mL4.0369 mL20.1845 mL
10 mM0.2018 mL1.0092 mL2.0184 mL10.0922 mL
20 mM0.1009 mL0.5046 mL1.0092 mL5.0461 mL
50 mM0.0404 mL0.2018 mL0.4037 mL2.0184 mL
100 mM0.0202 mL0.1009 mL0.2018 mL1.0092 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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