Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 113.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 276.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 588.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 125.00 |
Description | 1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. |
Targets&IC50 | Platelet:34.914 ug/mL |
Source |
Synonyms | Dehydrocorydalin, 13-Methylpalmatine |
Molecular Weight | 366.43 |
Formula | C22H24NO4 |
CAS No. | 30045-16-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 66 mg/mL(180.1 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
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Dehydrocorydaline 30045-16-0 Apoptosis Autophagy Chromatin/Epigenetic DNA Damage/DNA Repair MAPK Microbiology/Virology Proteases/Proteasome Caspase BCL p38 MAPK PARP Parasite Dehydrocorydalin Bcl-2 Family inhibit Inhibitor 13-Methylpalmatine poly ADP ribose polymerase inhibitor