Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Demethylwedelolactone

Catalog No. T5S0689Cas No. 6468-55-9

Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.

Demethylwedelolactone

Demethylwedelolactone

Purity: 100%
Catalog No. T5S0689Cas No. 6468-55-9
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.
Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$128In Stock
10 mg$213In Stock
25 mg$359In Stock
50 mg$535In Stock
1 mL x 10 mM (in DMSO)$123In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Demethylwedelolactone"

Select Batch
Purity:100%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.
Targets&IC50
Trypsin:3.0 μM
In vitro
demethylwedelolactone (DWEL) inhibited the anchorage-independent growth and also suppressed cell motility and cell invasion of MDA-MB-231 cells.DWEL reduced the activity and expression of matrix metalloproteinases (MMPs) involved in blocking the IκB-α/NFκB and MEK/ERK signaling pathways in MDA-MB-231 cells.?Furthermore, DWEL suppressed the metastasis and lung colonization of the tumor cells in the nude mice.?DWEL derivatives exert anti-invasive growth effect on breast cancer cells.
Chemical Properties
Molecular Weight300.22
FormulaC15H8O7
Cas No.6468-55-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (74.95 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3309 mL16.6545 mL33.3089 mL166.5445 mL
5 mM0.6662 mL3.3309 mL6.6618 mL33.3089 mL
10 mM0.3331 mL1.6654 mL3.3309 mL16.6545 mL
20 mM0.1665 mL0.8327 mL1.6654 mL8.3272 mL
50 mM0.0666 mL0.3331 mL0.6662 mL3.3309 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Demethylwedelolactone | purchase Demethylwedelolactone | Demethylwedelolactone cost | order Demethylwedelolactone | Demethylwedelolactone chemical structure | Demethylwedelolactone in vitro | Demethylwedelolactone formula | Demethylwedelolactone molecular weight