Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
2 mg | In stock | $ 143.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 396.00 | |
25 mg | In stock | $ 668.00 | |
50 mg | In stock | $ 953.00 | |
100 mg | In stock | $ 1,290.00 | |
500 mg | In stock | $ 2,590.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. |
Targets&IC50 | EGFR:1.48 nM, HER2:7.15 nM, HER4:2.49 nM |
Synonyms | S-22611 hydrochloride |
Molecular Weight | 596.48 |
Formula | C30H28Cl2FN5O3 |
CAS No. | 2071195-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (209.56 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Epertinib hydrochloride 2071195-74-7 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR HER inhibit Epidermal growth factor receptor S22611 Epertinib Epertinib Hydrochloride ErbB-1 HER1 S22611 Hydrochloride S 22611 S-22611 hydrochloride S-22611 S 22611 Hydrochloride S-22611 Hydrochloride Inhibitor inhibitor