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Fenebrutinib
Catalog No. TQ0242Cas No. 1434048-34-6
Alias GDC-0853
Fenebrutinib (GDC-0853) is a selective and noncovalent inhibitor of Bruton’s tyrosine kinase (Btk) with a Ki of 0.91 nM.
Fenebrutinib
Catalog No. TQ0242Alias GDC-0853Cas No. 1434048-34-6
Fenebrutinib (GDC-0853) is a selective and noncovalent inhibitor of Bruton’s tyrosine kinase (Btk) with a Ki of 0.91 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $36 | In Stock | |
| 2 mg | $52 | In Stock | |
| 5 mg | $84 | In Stock | |
| 10 mg | $153 | In Stock | |
| 25 mg | $345 | In Stock | |
| 50 mg | $515 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $123 | In Stock |
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Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
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IBT6A
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(±)-Zanubrutinib
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(±)-Zanubrutinib ((±)-BGB-3111) is a potent, orally available Bruton's tyrosine kinase (Btk) inhibitor, exhibiting superior oral bioavailability, higher exposure, and more complete target inhibition.
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CGI-1746
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CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.
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evobrutinib
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Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B -lymphocytes and macrophages. PreClinical research suggests it may be therapeutically useful in certain autoimmune diseases.
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Edralbrutinib
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- $30
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Purity:98.26%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fenebrutinib (GDC-0853) is a selective and noncovalent inhibitor of Bruton’s tyrosine kinase (Btk) with a Ki of 0.91 nM. |
| Targets&IC50 | BTK:0.91 nM (Ki) |
| Alias | GDC-0853 |
| Molecular Weight | 664.8 |
| Formula | C37H44N8O4 |
| Cas No. | 1434048-34-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (30.09 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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