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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $67 | In Stock | |
5 mg | $163 | In Stock | |
10 mg | $263 | In Stock | |
25 mg | $447 | In Stock | |
50 mg | $646 | In Stock | |
100 mg | $888 | In Stock | |
500 mg | $1,790 | In Stock |
Description | 1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells. |
Alias | Flavokavain B, Flavokawin B, 2'-Hydroxy-4',6'-Dimethoxychalcone |
Molecular Weight | 284.31 |
Formula | C17H16O4 |
Cas No. | 1775-97-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 65 mg/mL (228.62 mM), Sonication is recommended. ![]() Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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