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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $41 | In Stock | |
10 mg | $64 | In Stock | |
25 mg | $143 | In Stock | |
50 mg | $268 | In Stock | |
100 mg | $405 | In Stock | |
200 mg | $585 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Formoterol fumarate (Eformoterol Hemifumarate), an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma. |
In vitro | In guinea pig lungs, Formoterol at a concentration of 100 mg/mL inhibits Platelet-Activating Factor (PAF)-induced eosinophil aggregation and suppresses Porcine Pancreatic Elastase (PPE) activity for 2-4 hours. In conscious guinea pigs, Formoterol dose-dependently inhibits histamine-induced plasma protein leakage and bronchoconstriction. Significant inhibition of histamine-induced effects was observed at doses of 10 mg/mL and 100 mg/mL. Additionally, a higher concentration of Formoterol is required to inhibit neutrophil aggregation (induced by Lipopolysaccharides) compared to its ability to suppress granulocyte-independent PPE (induced by histamine). |
In vivo | Formoterol is a high-affinity, selective β2-adrenergic receptor agonist that effectively relaxes airway smooth muscles. Similar to salbutamol and salmeterol, it relaxes guinea pig trachea and human bronchi in vitro in a concentration-dependent manner and inhibits the release of antigen-induced inflammatory mediators in human lung slices. |
Alias | Formoterol Hemifumarate, NSC 299587, Eformoterol Hemifumarate, CGP 25827A, Eformoterol, YM 08316 |
Molecular Weight | 402.4 |
Formula | C19H24N2O4·1/2C4H4O4 |
Cas No. | 43229-80-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 74 mg/mL (183.9 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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