Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 128.00 | |
5 mg | In stock | $ 272.00 | |
10 mg | In stock | $ 437.00 | |
25 mg | In stock | $ 723.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,380.00 | |
500 mg | In stock | $ 2,760.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 393.00 |
Description | GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. |
In vitro | GET73 (1 μM, 10 μM; 1 hour) 1 hour before and during chronic ethanol exposure prevents ethanol-induced a reduction of cell viability, an alteration of cytoskeleton, an increase of reactive oxygen species production?and a decrease in extracellular glutamate levels. |
In vivo | GET73 exerts an anxiolytic effect in Sprague-Dawley rats exposed to the elevated plus maze (EPM) test. |
Synonyms | Gamma hydroxybutyric acid analogue, GET 73 |
Molecular Weight | 275.27 |
Formula | C13H16F3NO2 |
CAS No. | 202402-01-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 97 mg/mL (352.38 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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GET73 202402-01-5 Neuroscience GluR neuroprotective anti-alcohol inhibit γ-hydroxybutyric acid mGluR5 GHB GET-73 Gamma hydroxybutyric acid analogue Inhibitor GET 73 anxiolytic glutamate inhibitor