GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.

Monocarboxylate transporter (MCT1) inhibitor (pKi = 7.6. Exhibits approximately 10-fold selectivity for MCT1 over MCT2 and no significant activity against MCT3 or 4. Inhibits graft versus host response and prolongs cardiac graft survival in a rat model. Immunosuppressant. Also inhibits brain penetration of GHB analog HOCPCA.

Valiloxibic acid is a prodrug of γ-Hydroxybutyric acid (GHB).GHB is a naturally occurring neurotransmitter and a psychoactive drug, it acts on the GHB receptor and is a weak agonist at the GABAB receptor.

NCS-356 is a GHB receptor agonist.

ligand of γ-hydroxybutyric acid (GHB) receptor

2-Hydroxy-3-methylbutyric acid is a structural analog of GHB, a naturally occurring substance found in the central nervous system, and a nootropic.

UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.

2-Hydroxy-3-methylbutyric acid is a structural analog of GHB, a naturally occurring substance found in the central nervous system, and a nootropic.

HOCPCA is an effective and selective ligand for the GHB binding sites that acts by binding with 27 times better affinity than GHB itself and crossing the blood-brain barrier in vitro and in vivo.

NCS-356 sodium is a GHB receptor agonist.

NCS-356 sodium monohydrate is a GHB receptor agonist.