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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $128 | In Stock | |
5 mg | $272 | In Stock | |
10 mg | $437 | In Stock | |
25 mg | $723 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,380 | In Stock | |
500 mg | $2,760 | In Stock | |
1 mL x 10 mM (in DMSO) | $393 | In Stock |
Description | GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. |
In vitro | GET73 (1 μM, 10 μM; 1 hour) 1 hour before and during chronic ethanol exposure prevents ethanol-induced a reduction of cell viability, an alteration of cytoskeleton, an increase of reactive oxygen species production and a decrease in extracellular glutamate levels. |
In vivo | GET73 exerts an anxiolytic effect in Sprague-Dawley rats exposed to the elevated plus maze (EPM) test. |
Alias | Gamma hydroxybutyric acid analogue, GET 73 |
Molecular Weight | 275.27 |
Formula | C13H16F3NO2 |
Cas No. | 202402-01-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 97 mg/mL (352.38 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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