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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $79 | In Stock | |
2 mg | $97 | In Stock | |
5 mg | $162 | In Stock | |
10 mg | $253 | In Stock | |
25 mg | $429 | In Stock | |
50 mg | $623 | In Stock | |
100 mg | $882 | In Stock |
Description | Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. |
In vitro | Oscillatory behaviour was abolished by Gap 26 at concentrations of 100-300 microM (IC50 of 20-30 microM), without a change in average tone. No synergy was evident between peptides corresponding to the extracellular loops, and cytoplasmic loop peptides were biologically inactive [1]. Photoliberating InsP(3) in a single cell within a confluent culture triggered an intercellular calcium wave, which was inhibited by the connexin mimetic peptide gap 26 [2]. |
Molecular Weight | 1550.78 |
Formula | C70H107N19O19S |
Cas No. | 197250-15-0 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 10 mM | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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