Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 61.00 | |
10 mg | In stock | $ 116.00 | |
25 mg | In stock | $ 211.00 | |
50 mg | In stock | $ 289.00 | |
100 mg | In stock | $ 429.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 67.00 |
Description | Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen. |
In vivo | Guggulsterone E&Z inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP, and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases, inhibition of Akt, and activation of JNK.?Guggulsterone E&Z modulates the expression of gene products involved in metastasis (MMP-9, COX-2, and VEGF) of tumor cells. |
Source |
Synonyms | Guggulsterone E&Z |
Molecular Weight | 312.45 |
Formula | C21H28O2 |
CAS No. | 95975-55-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20.83 mg/mL (66.67 mM)
You can also refer to dose conversion for different animals. More
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Guggulsterone 95975-55-6 Apoptosis Autophagy Cytoskeletal Signaling MAPK Metabolism PI3K/Akt/mTOR signaling Proteases/Proteasome Akt Caspase JNK FXR Z/E-Guggulsterone Inhibitor inhibit Protein kinase B Guggulsterone E&Z PKB NR1H4 inhibitor