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JK-P3

Catalog No. T4425Cas No. 942655-44-9

JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

JK-P3

JK-P3

Purity: 100%
Catalog No. T4425Cas No. 942655-44-9
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Pack SizePriceAvailabilityQuantity
5 mg$33In Stock
10 mg$59In Stock
25 mg$133In Stock
50 mg$238In Stock
100 mg$353In Stock
200 mg$493In Stock
1 mL x 10 mM (in DMSO)$37In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endo
Targets&IC50
VEGFR2:7.8 μM
Chemical Properties
Molecular Weight323.35
FormulaC18H17N3O3
Cas No.942655-44-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (185.56 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0926 mL15.4631 mL30.9262 mL154.6312 mL
5 mM0.6185 mL3.0926 mL6.1852 mL30.9262 mL
10 mM0.3093 mL1.5463 mL3.0926 mL15.4631 mL
20 mM0.1546 mL0.7732 mL1.5463 mL7.7316 mL
50 mM0.0619 mL0.3093 mL0.6185 mL3.0926 mL
100 mM0.0309 mL0.1546 mL0.3093 mL1.5463 mL

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