Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 222.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 589.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. |
Targets&IC50 | VEGFR2:7.8 μM |
Molecular Weight | 323.35 |
Formula | C18H17N3O3 |
CAS No. | 942655-44-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (185.56 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JK-P3 942655-44-9 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Inhibitor HUVEC Anti-angiogenesis FGFR JK P3 Fibroblast growth factor receptor JKP3 Anti-cancer inhibit Endothelial cells JK-P-3 Vascular endothelial growth factor receptor inhibitor