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JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $33 | In Stock | |
10 mg | $59 | In Stock | |
25 mg | $133 | In Stock | |
50 mg | $238 | In Stock | |
100 mg | $353 | In Stock | |
200 mg | $493 | In Stock | |
1 mL x 10 mM (in DMSO) | $37 | In Stock |
Description | JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endo |
Targets&IC50 | VEGFR2:7.8 μM |
Molecular Weight | 323.35 |
Formula | C18H17N3O3 |
Cas No. | 942655-44-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (185.56 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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