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JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $30 | In Stock | |
5 mg | $46 | In Stock | |
10 mg | $68 | In Stock | |
25 mg | $133 | In Stock | |
50 mg | $197 | In Stock | |
100 mg | $287 | In Stock | |
1 mL x 10 mM (in DMSO) | $55 | In Stock |
Description | JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM). |
In vitro | JQEZ5 inhibits colony formation of primary human CD34+ chronic myelogenous leukemia (CML) stem/progenitor cells but not non-cancerous human CD34+ hematopoietic stem/progenitor cells when used at concentrations ranging from 0.5 to 5 μM |
Molecular Weight | 542.68 |
Formula | C30H38N8O2 |
Cas No. | 1913252-04-6 |
Smiles | CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(nc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(C)CC1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (46.07 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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