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Cat No. | Product Name | Synonyms | Targets |
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T10341 | Antitumor agent-19 | Others | |
Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells. | |||
T10342 | Antitumor agent-2 | Others | |
Antitumor agent-2 has anti-inflammatory and anti-tumor activity and can be used to study cancer. | |||
T3389 | Antitumor agent-21 | TRX818 | Others |
Antitumor agent-21 (TRX818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. | |||
T39889 | Antitumor agent-23 | ||
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respe... | |||
T39523 | Antitumor agent-28 | ||
Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and dem... | |||
T14296 | Antitumor agent-3 | Others | |
Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient. | |||
T12443 | Antitumor agent-4 | Others | |
Antitumor agent-4 is a butenylphenyl phosphate derivative, is an agent of mammary cancer and anovulatory sterility. | |||
T63513 | Antitumor agent-71 | ||
Antitumor Agent-71 is an antitumor compound that exhibits an inhibitory effect on tubulin aggregation. antitumor Agent-71 possesses an anti-proliferative effect with IC50 values ranging from 3.98-15.70 μM against tumor c... | |||
T72523 | Antitumor agent-46 | ||
Antitumor agent-46 is an anti-tumor agent. Antitumor agent-46 demonstrates markedly higher antiproliferative activity on MCF-7 cells with an IC 50 value of 2.08 µM . | |||
T62480 | Antitumor agent-51 | ||
Antitumor agent-51 is effective and selective in inhibiting the growth and migration of osteosarcoma cells, acting on MNNG/HOS cells (IC50: 21.9 nM). antitumor agent-51 is less toxic and extremely bioavailable. | |||
T74601 | Antitumor photosensitizer-3 | ||
Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity c... | |||
T83011 | Antitumor agent-105 | ||
Antitumor Agent-105 (Compound 37) exhibits antitumor activity, demonstrating inhibition of A549, H1299, H460, HCT116, and MDA-MB-231 cells with respective IC50 values of 6.7, 8.3, 4.3, 4.4, and 6.7 μM [1]. | |||
T79466 | Antitumor agent-111 | c-Met/HGFR | |
Antitumor Agent-111 (Compound 46), a c-Met kinase inhibitor (IC50 = 46 nM), exhibits both antitumor and antiproliferative effects. It impedes the cell cycle at the G0/G1 phase and induces apoptosis [1]. | |||
T64111 | Antitumor agent-76 | ||
Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects. | |||
T64128 | Antitumor agent-56 | ||
Antitumor agent-56 is an orally active triptolide derivative that significantly inhibits melanoma growth, exhibiting anti-tumour, anti-inflammatory and NO-releasing effects. | |||
T79463 | Antitumor agent-110 | Apoptosis | |
Antitumor Agent-110 (Compound 13), an imidazotetrazine anticancer agent, exhibits excellent permeability. It halts the cell cycle at the G2/M phase and induces apoptosis [1]. | |||
T79582 | Antitumor agent-116 | MELK | |
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis. It demonstrates binding affinity for the MELK receptor [1]. | |||
T79265 | Antitumor agent-104 | PARP | |
Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme activity and reduction of PAR protein levels. Additionally, ... | |||
T74950 | Antitumor agent-73 | STAT | |
Antitumor Agent-73, a derivative of Diosgenin, both impedes STAT3 signaling and exogenously stimulates Pdia3/ERp57. This compound demonstrates significant antineoplastic efficacy, exhibiting potency against diverse cance... | |||
T83008 | Antitumor agent-119 | ||
Antitumor agent-119 (compound 13K), a 2-benzoxazolyl hydrazone derivative, exhibits anticancer capabilities by impeding the proliferation of Burkitt, CCRF-CEM, HeLa, and HT-29 cells, with respective IC50 values of 30 nM,... | |||
T79711 | Antitumor photosensitizer-4 | Apoptosis | |
Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen speci... | |||
T75078 | Antitumor agent-86 | Akt | |
Antitumor agent-86 (compound 5a) demonstrates efficacy against MCF-7 breast cancer cells, manifesting an inhibitory concentration (IC 50) of 2.62 µM. It promotes apoptosis and cell cycle arrest, exhibiting antineoplastic... | |||
T62510 | Antitumor agent-75 | ||
Antitumor agent-75 is a novel and potent antitumor agent. antitumor agent-75 has cytotoxic effects on cancer and normal human cell lines. antitumor agent-75 in combination with antitumor agent-74 exhibits a highly select... | |||
T61806 | Antitumor agent-44 | ||
Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human adenocarcinoma cells. Moreover, Antitumor agent-44 demonstr... | |||
T60505 | Antitumor agent-43 | ||
Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase. Antitumor agent-43 has an IC 50 of 0.5 μM for T-24 cells [1]. | |||
T72571 | Antitumor agent-84 | ||
Antitumor Agent-84, a G-quadruplex (G4)-ligand, stabilizes various G4-DNA structures, demonstrating highly effective antitumor properties. | |||
T61186 | Antitumor agent-57 | ||
Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound. It effectively inhibits tumor cell growth, induces ROS generation, and promotes cell apoptosis [1]. | |||
T63494 | Antitumor agent-60 | ||
Antitumor agent-60 is a potent antitumor agent that targets the RAS-RAF signaling pathway and binds to CRAF (Kd: 721.3 nM). antitumor agent-60 increases p53 and ROS levels in cancer cells, resulting in oval and irregular... | |||
T64022 | Antitumor agent-37 | ||
Antitumor agent-37 exhibits potent anti-proliferative and anti-metastatic effects. antitumor agent-37 induces severe DNA damage, leading to high expression of γ-H2AX and p53. antitumor agent-37 induces apoptosis by explo... | |||
T62835 | Antitumor agent-54 | ||
Antitumor agent-54 (Compound C11) is a 14-3-3η protein inhibitor (KD: 35 μM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S ph... | |||
T72561 | Antitumor agent-82 | ||
Antitumor Agent-82 is a potent anti-tumor compound that exhibits anti-proliferative activity and induces cell autophagy through the ATG5/ATG7 signaling pathway. | |||
T83004 | Antitumor agent-39 | ||
Antitumor Agent-39 is a peptide-based compound with anticancer properties[1]. | |||
T61616 | Antitumor agent-38 | ||
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microt... | |||
T72575 | Antitumor agent-90 | ||
Antitumor Agent-90 exhibits cytotoxic effects against PC 14 and MKN 45 cells, indicating its potential utility in cancer research. | |||
T72572 | Antitumor agent-85 | ||
Antitumor agent-85, a G-quadruplex (G4)-ligand, stabilizes various G4-DNA structures and possesses potent anti-tumor properties. | |||
T60421 | Antitumor agent-68 | ||
Antitumor agent-68 is a potent tubulin inhibitor that exhibits good antitumor activity with IC 50 s of 3.6 and 3.8 μM for cervical cancer cells line HeLa and breast cancer cells line MCF-7 cells, respectively. Antitumor ... | |||
T63271 | Antitumor agent-62 | ||
Antitumor agent-62 is an NO-releasing antitumor agent that exhibits antiproliferative effects on cancer cells, activates the mitochondrial apoptosis pathway, and is capable of blocking the cell cycle to G2/M phase. | |||
T64014 | Antitumor agent-58 | ||
Antitumor agent-58 is an antitumour agent that effectively inhibits colony formation and cell migration in MGC-803 cells and induces mitochondrial dysfunction in MGC-803 cells. Antitumor agent-58 exhibited potent inhibit... | |||
T83006 | Antitumor agent-29 | ||
Antitumor agent-29 is a hepatocyte-targeting prodrug with demonstrated efficacy and minimal toxicity in anticancer applications. | |||
T72552 | Antitumor agent-88 | ||
Antitumor agent-88, a competitive inhibitor of CYP1A1 (K i: 1.4 μM), demonstrates significant antimitotic activity by arresting cells in the G2/M phase and disrupting the microtubule network and cytoskeleton in CYP1A1-ex... | |||
T74393 | Antitumor agent-36 | ||
Antitumor agent-36 exhibits strong anti-proliferative and anti-metastasis capabilities, causing significant DNA damage that results in elevated levels of γ-H2AX and p53. It promotes tumor cell apoptosis via the mitochond... | |||
T64071 | Antitumor agent-42 | ||
Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects. | |||
T72560 | Antitumor agent-81 | ||
Antitumor agent-81, a P62-RNF168 agonist with low cytotoxicity, enhances the P62-RNF168 interaction, leading to decreased RNF168-mediated H2A ubiquitination and impaired homologous recombination-mediated DNA repair. Addi... | |||
T83010 | Antitumor agent-106 | ||
Antitumor Agent-106 (Compound 42) is a potent anticancer compound, demonstrating significant inhibitory activity (IC50 = 4.2-6.6 µM) against lung and colon cancer cell lines [1]. | |||
T64034 | Antitumor agent-45 | ||
Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis. | |||
T78912 | Antitumor agent-113 | Apoptosis | |
Antitumor Agent-113 exhibits cytotoxicity in A549 cells, with an IC50 of 46.60 μM, and induces apoptosis, making it applicable for research in non-small cell lung cancer [1]. | |||
T74768 | Antitumor agent-92 | Apoptosis | |
Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1]. | |||
T82997 | Antitumor photosensitizer-2 | ||
Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, representing a promising candidate for photodynamic ... | |||
T82998 | Antitumor photosensitizer-1 | ||
Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, positioning it as a promising new candidate for photodynamic therap... | |||
T79434 | Antitumor agent-103 | Apoptosis | |
Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties. This compound halts the cell cycle at the G0/G1 phase, augments nitric oxide (NO) production, and... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83000 | Antitumor agent-89 | ||
Antitumor agent-89 (Compd OTS-5), a naturally occurring compound, exhibits weak inhibitory activity against fMLP-induced superoxide generation [1]. | |||
TN1932 | Microhelenin C | Others | |
Microhelenin C has significant antileukemic activity. | |||
T40179 | Sodium Camptothecin | DNA/RNA Synthesis | |
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i... | |||
TN1148 | Isopsoralenoside | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Antibacterial | |
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects. | |||
T11363 | Ganoderic acid F | Others | |
Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si... | |||
T38815 | Millepachine | Apoptosis | |
Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells. | |||
TN1807 | Isoverticine | BCL , Caspase | |
Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity. | |||
T3S2381 | Perillene | 3-Isohexenylfuran,Perillen | Others , Antibacterial |
Perillene (3-Isohexenylfuran) is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli. | |||
T5814 | Aurantiamide | TMC-58B | p38 MAPK , NF-κB |
Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula... | |||
TN2085 | Piperlonguminine | Anti-infection , Antibacterial , Antifungal | |
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl... | |||
T2210 | Genipin | (+)-Genipin | Others , Autophagy |
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis. | |||
T1032 | Erythromycin | E-Mycin | ribosome , Antibacterial , Antibiotic |
Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity. | |||
TQ0165 | Arglabin | (+)-Arglabin | NOD-like Receptor (NLR) , Transferase , NOD , Autophagy |
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T5A2461 | Bufotalin | Bufotaline | Apoptosis , Others , Reactive Oxygen Species |
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads. | |||
T2957 | Arctigenin | (-)-Arctigenin | Apoptosis , MMP , Influenza Virus , Autophagy |
(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plan... | |||
T6830 | Epoxomicin | BU-4061T,BU-4061T,Aids010837 | Apoptosis , Proteasome |
Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited... | |||
T1035 | Hesperidin | Hesperetin 7-rutinoside,Cirantin | Apoptosis , Reactive Oxygen Species , Endogenous Metabolite , Autophagy |
Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity. | |||
T1335 | Mycophenolic acid | Mycophenolate,RS-61443 | Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal |
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. | |||
T2S2108 | Coixol | 6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA | Others , Antibacterial |
1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate fo... | |||
T9605 | Sangivamycin | BA-90912,NSC 65346 | Nucleoside Antimetabolite/Analog , PKC |
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers. | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T17155 | Trabectedin | Ecteinascidin 743,ET-743 | Apoptosis , Reactive Oxygen Species |
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0... | |||
T2764 | (S)-10-Hydroxycamptothecin | 10-Hydroxycamptothecin,10-HCPT | Apoptosis , Topoisomerase |
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma. | |||
T1882 | Meisoindigo | N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III | Apoptosis |
Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML). | |||
T22455 | Vindesine sulfate | DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS | Others |
Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule... | |||
T7203 | Oglufanide | L-Glutamyl-L-tryptophan,H-Glu-Trp-OH | VEGFR , HCV Protease , Endogenous Metabolite |
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF). | |||
T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
TN1025 | 3,29-O-Dibenzoyloxykarounidiol | Others | |
3,29-O-Dibenzoyloxykarounidiol is a natural product with regulate blood sugar level, has potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) induced by tumor promoter 12-O-tetradecanoylphorbol-13-aceta... | |||
TN6732 | Oenothein B | Apoptosis , HCV Protease , Antibacterial , Antifungal | |
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. | |||
TN7217 | 4,6-Benzilidine-D-Glucose | ||
4,6-Benzilidine-D-Glucose is a clinical antitumor compound showing antitumor activity in rats with chemically induced hepatocellular carcinoma. | |||
T67047 | 2-Acetyl-3-ethylpyrazine | Endogenous Metabolite | |
2-Acetyl-3-ethylpyrazine has antitumor activity. | |||
T4S1848 | Tubeimoside II | Tubeimoside-B | Others |
Tubeimoside II (also known as Tubeimoside-B), a natural oleanane-type triterpenoid saponin analogue, exhibits anti-inflammatory, antitumor, and antitumor-promoting properties. | |||
T3S1457 | Palmaturbine | Palmatrubin,Palmatrubine | Others |
Palmaturbine (Palmatrubine) shows high antitumor activity. | |||
T1257 | Bestatin | Ubenimex | Others , Aminopeptidase , Antibacterial , Antibiotic , LTR |
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin... | |||
T2736 | Sodium Demethylcantharidate | Sodium norcantharidin | Others , Endogenous Metabolite |
Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity. | |||
TN7123 | Enmein, 13-deoxy-19-hydroxy-, (19R)- | Others | |
Enmein, 13-deoxy-19-hydroxy-, (19R)- is an Enmein-type diterpene derivative and can be used in the preparation of antitumor drugs. | |||
T11354 | Gambogellic acid | ||
Gambogellic acid is an xanthone compound obtained from Garcinia cambogia and processed Gambog, is antitumor activity and cytotoxicity. | |||
T6473 | Dioscin | CCRIS 4123,Collettiside III,Saponin | Apoptosis , Autophagy |
Dioscin (Collettiside III) is a saponin with antitumor activities. | |||
T3366 | Cephalotaxine | ZINC19795976,(-)-Cephalotaxine,Cephalotaxlen | Antiviral , Influenza Virus |
Cephalotaxine (ZINC19795976) is an antiviral and an antitumor agent. | |||
T7049 | Herniarin | Methyl umbelliferyl ether,Ayapanin,7-Methoxycoumarin,Herniarine | Others |
Herniarin (Ayapanin) is a natural coumarin with antitumor effect. | |||
T5581 | 6-(γ,γ-Dimethylallylamino)purine | N6-(2-lsopentenyl)adenine,Triacanthine | Others |
6-(γ,γ-Dimethylallylamino)purine (Triacanthine), which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic. | |||
TN7250 | Torachrysone Triglucoside | 1-[8-[(O-β-D-Glucopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]-1-hydroxy-6-methoxy-3-methyl-2-naphthalenyl]ethanone | Others |
Torachrysone Triglucoside is a glucoside isolated from cassia seeds with potential antitumor activity. | |||
T2217 | Cephalomannine | Baccatin III | Microtubule Associated |
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity. | |||
T22286 | Cyanosafracin B | Cyanoquinonamine,CBR28-1 | Others |
Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug). | |||
T2728 | Limonin | Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,Obaculactone,Citrolimonin | Apoptosis , HIV Protease , Endogenous Metabolite |
Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability. | |||
T12971 | Solanidine | Others | |
Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation. | |||
TMS1743 | Salvigenin | MAO , Autophagy , ROS Kinase | |
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects. | |||
TN6097 | Girinimbine | Girinimbin | Apoptosis , Antioxidant , Antibacterial |
Girinimbine (Girinimbin) is a carbazole alkaloid isolated from the plants M. koenigii, M. koenigii and Murraya koenigii.Girinimbine has a wide range of biological effects, including apoptosis, antitrypanosomal, antiplate... | |||
T2997 | Rhein | Rheinic Acid,Monorhein,NSC 38629,Rheic Acid,Rhubarb yellow | Reactive Oxygen Species , Antibacterial , Autophagy |
Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01461 | EMAP-II/AIMP1 Protein, Human, Recombinant (His) | Human | E. coli |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro... | |||
TMPY-05227 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-01621 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-00265 | Interferon alpha 2/IFNA2 Protein, Human, Recombinant | Human | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-00007 | Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant | Mouse | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-03153 | IL-27 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells, and dendritic cells. IL-27 protein is also referred to as the IL-12 p35-related protein, p28, is one subunit of a het... | |||
TMPY-03142 | IL-27 Protein, Human, Recombinant (His) | Human | CHO |
IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells, and dendritic cells. IL-27 protein is also referred to as the IL-12 p35-related protein, p28, is one subunit of a het... | |||
TMPY-01423 | OX40/TNFRSF4 Protein, Human, Recombinant (His) | Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-00463 | ENPP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-02778 | ENPP2 Protein, Human, Recombinant (His) | Human | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-02031 | B7-H3 Protein, Human, Recombinant (His) | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-04262 | B7-H3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-04064 | B7-H3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-06983 | IFN gamma Protein, Human, Recombinant (E. coli) | Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-01714 | IFN gamma Protein, Human, Recombinant | Human | CHO |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-05641 | B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-03356 | IFN gamma Protein, Mouse, Recombinant | Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-02827 | IFN gamma Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-01872 | IL-28B Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda... | |||
TMPY-01608 | Decorin Protein, Human, Recombinant (His) | Human | HEK293 |
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p... | |||
TMPH-02745 | Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. | |||
TMPK-00126 | CLEC4A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effe... | |||
TMPH-02204 | THRB Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli... | |||
TMPK-00127 | CLEC4A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effe... | |||
TMPK-00249 | TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL... | |||
TMPK-00248 | TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL... | |||
TMPJ-00008 | CXCL10 Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX... | |||
TMPH-00943 | AP2M1 Protein, Human, Recombinant (His) | Human | E. coli |
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction... | |||
TMPJ-00076 | IL-28B Protein, Human, Recombinant | Human | Human Cells |
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to pla... | |||
TMPY-03015 | EMAP-II/AIMP1 Protein, Mouse, Recombinant | Mouse | E. coli |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro... | |||
TMPY-03424 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-05428 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-06296 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-03677 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-05463 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-00553 | TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-03319 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) | Rhesus | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-00096 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant | Rhesus | Yeast |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-06407 | Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-02661 | Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-03735 | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero... | |||
TMPY-05091 | OX40/TNFRSF4 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-05020 | OX40/TNFRSF4 Protein, Mouse, Recombinant | Mouse | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-02368 | OX40/TNFRSF4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-06906 | OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-05339 | OX40/TNFRSF4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-04993 | OX40/TNFRSF4 Protein, Mouse, Recombinant (rFc) | Mouse | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-04718 | OX40/TNFRSF4 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-06875 | OX40/TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-04723 | OX40/TNFRSF4 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L6700 | Anti-Tumor Natural Product Library | 1800 compounds | |
A unique collection of 1800 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2180 | Anti-Cancer Compound Library Plus | 1468 compounds | |
Well-chosen 1468 anti-tumor compounds with unique structures; | |||
L2152 | Targeted Therapy Drug Library | 121 compounds | |
121 tumor-targeted drugs that can be used for high-throughput and high-content screening. | |||
L9610 | Cyclic Peptide Library | 58 compounds | |
58 species of cyclic peptide molecules for high-throughput and high-content screening; | |||
L2521 | Glycolysis Compound Library | 560 compounds | |
560 glycolysis-related active compounds for high-throughput and high-content screening. | |||
L6140 | Saccharide and Glycoside Natural Product Library | 364 compounds | |
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L6800 | Chinese Pharmacopoeia Natural Product Library | 2070 compounds | |
A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study; | |||
L9300 | Macrocyclic Compound Library | 216 compounds | |
216 macrocyclic compounds of known activity for high-throughput, high-content screening; |