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9-cis-Retinoic Acid
🥰Excellent
Catalog No. T21497Cas No. 5300-03-8
Alias Alitretinoin
9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors.
9-cis-Retinoic Acid
🥰Excellent
Purity: 98.32%
Catalog No. T21497Alias AlitretinoinCas No. 5300-03-8
9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $78 | In Stock | |
| 5 mg | $123 | In Stock | |
| 10 mg | $198 | In Stock | |
| 25 mg | $396 | In Stock | |
| 50 mg | $619 | In Stock | |
| 100 mg | $993 | In Stock |
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CitedSelect Batch
Purity:98.32%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors. |
| In vitro | In CA 9-22 and NA cells, 9-cis-Retinoic acid (1 μM, 10 μM; 0 day, 1 day, 3 days, 5 days) significantly decreased proliferation[1]. |
| In vivo | In male C57BL/6J mice (6-8 weeks old; 19-22 g), following bile duct ligation, treatment with 9-cis-Retinoic Acid (1 mg/kg; intravenous injection; once daily; for 10 days) significantly decreased serum ALT and AST levels and alleviated hepatic necrosis[3]. |
| Alias | Alitretinoin |
| Molecular Weight | 300.44 |
| Formula | C20H28O2 |
| Cas No. | 5300-03-8 |
| Smiles | C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (49.93 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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