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Imiquimod maleate
🥰Excellent
Catalog No. T22862Cas No. 896106-16-4
Alias R837 maleate, R 837 maleate
Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies.
Imiquimod maleate
🥰Excellent
Catalog No. T22862Alias R837 maleate, R 837 maleateCas No. 896106-16-4
Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $29 | In Stock | |
| 50 mg | $39 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies. |
| In vivo | In animal models, Imiquimod maleate stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α, and inducing proliferation and differentiation of B lymphocytes. [1] |
| Alias | R837 maleate, R 837 maleate |
| Molecular Weight | 356.38 |
| Formula | C18H20N4O4 |
| Cas No. | 896106-16-4 |
| Smiles | C(=C\C(O)=O)\C(O)=O.C(C(C)C)N1C=2C=3C(N=C(N)C2N=C1)=CC=CC3 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 1 mg/mL (2.81 mM.), Sonication is recommended. DMSO: 20 mg/mL (56.12 mM.), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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