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Imiquimod hydrochloride

🥰Excellent
Catalog No. T22091Cas No. 99011-78-6
Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl

Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].

Imiquimod hydrochloride

Imiquimod hydrochloride

🥰Excellent
Purity: 99.18%
Catalog No. T22091Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HClCas No. 99011-78-6
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
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50 mg$33In Stock
100 mg$45In Stock
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Purity:99.18%
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Product Introduction

Bioactivity
Description
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
In vivo
Imiquimod hydrochloride stimulates innate immune responses by inducing synthesis and release of cytokines, including interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)[1].
AliasR-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl
Chemical Properties
Molecular Weight276.77
FormulaC14H17ClN4
Cas No.99011-78-6
SmilesCl.CC(C)Cn1cnc2c(N)nc3ccccc3c12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Methanol: 15 mg/mL (54.20 mM), Sonication is recommended.
DMSO: 5 mg/mL (18.07 mM), Sonication and heating are recommended.
Ethanol: 1 mg/mL (3.61 mM), Sonication is recommended.
H2O: 2 mg/ml (7.23 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/H2O/DMSO/Methanol
1mg5mg10mg50mg
1 mM3.6131 mL18.0655 mL36.1311 mL180.6554 mL
H2O/DMSO/Methanol
1mg5mg10mg50mg
5 mM0.7226 mL3.6131 mL7.2262 mL36.1311 mL
DMSO/Methanol
1mg5mg10mg50mg
10 mM0.3613 mL1.8066 mL3.6131 mL18.0655 mL
Methanol
1mg5mg10mg50mg
20 mM0.1807 mL0.9033 mL1.8066 mL9.0328 mL
50 mM0.0723 mL0.3613 mL0.7226 mL3.6131 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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