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Imiquimod hydrochloride
Catalog No. T22091Cas No. 99011-78-6
Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
Imiquimod hydrochloride
Catalog No. T22091Alias R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HClCas No. 99011-78-6
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $33 | In Stock | |
| 100 mg | $45 | In Stock |
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CitedChloroquine
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Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine also has anti-SARS-CoV-2 (COVID-19) activity and anti-HIV-1 activity.
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CitedResiquimod Cited
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Resiquimod (R848) is a Toll-like receptor 7/8 (TLR7/TLR8) agonist that induces cytokine upregulation. Resiquimod is an immunomodulator with antitumor and antiviral activity.
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CitedImiquimod Cited
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Purity:99.18%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2]. |
| In vivo | Imiquimod hydrochloride stimulates innate immune responses by inducing synthesis and release of cytokines, including interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)[1]. |
| Alias | R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl |
| Molecular Weight | 276.77 |
| Formula | C14H17ClN4 |
| Cas No. | 99011-78-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Methanol: 15 mg/mL (54.20 mM), Sonication is recommended. DMSO: 5 mg/mL (18.07 mM), Sonication and heating are recommended. Ethanol: 1 mg/mL (3.61 mM), Sonication is recommended. H2O: 2 mg/ml (7.23 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
Ethanol/H2O/DMSO/Methanol
H2O/DMSO/Methanol
DMSO/Methanol
Methanol
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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