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Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $33 | In Stock | |
100 mg | $45 | In Stock |
Description | Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 [1] [2]. |
In vivo | Imiquimod hydrochloride stimulates innate immune responses by inducing synthesis and release of cytokines, including interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)[1]. |
Alias | R-837 hydrochloride, R837 hydrochloride, R 837 hydrochloride, Imiquimod HCl |
Molecular Weight | 276.77 |
Formula | C14H17ClN4 |
Cas No. | 99011-78-6 |
Smiles | Cl.CC(C)Cn1cnc2c(N)nc3ccccc3c12 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||||||||||||
Solubility Information | Methanol: 15 mg/mL (54.20 mM), Sonication is recommended. DMSO: 5 mg/mL (18.07 mM), Sonication and heating are recommended. Ethanol: 1 mg/mL (3.61 mM), Sonication is recommended. H2O: 2 mg/ml (7.23 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
Ethanol/H2O/DMSO/Methanol
H2O/DMSO/Methanol
DMSO/Methanol
Methanol
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