Shopping Cart
- Remove All
Your shopping cart is currently empty
Oenothein B
😃Good
Catalog No. TN6732Cas No. 104987-36-2
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
Oenothein B
😃Good
Catalog No. TN6732Cas No. 104987-36-2
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $298 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Oenothein B"
Dimethyl sulfoxide
Cited
Methyl Sulfoxide, DMSO
T034167-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
- $45
Size
QTY
CitedNeomycin sulfate Cited
Framycin sulfate
T09501405-10-3
Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.
- $43
Size
QTY
CitedTributyrin
NSC-661583, NSC661583, NSC 661583
T1967660-01-5
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
- $50
Size
QTY
Sulfamethoxazole sodium
Ro 4-2130 sodium
T81394563-84-2
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic.
- $32
Size
QTY
Doxycycline Cited
Vibramycin, Doxytetracycline, Doxycyclinum, Doxiciclina
T1687564-25-0
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.
- $45
Size
QTY
CitedKanamycin sulfate
Ophtalmokalixan, Kanamycin monosulfate, Kanamycin A monosulfate
T079325389-94-0
Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.
- $41
Size
QTY
Stavudine
Sanilvudine, NSC 163661, d4T, BMY-27857
T14043056-17-5
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
ApoptosisAutophagyHIV ProteaseNOD-like Receptor (NLR)Nucleoside Antimetabolite/AnalogReverse Transcriptase
- $33
Size
QTY
Ampicillin sodium Cited
Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral
T638669-52-3
Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium (Domicillin) inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan synthesis, a critical component of the bacterial cell wall.
- $45
Size
QTY
CitedDextran sulfate sodium salt (MW 4500-5500) Cited
DSS, Dextran sulfate sodium salt (MW 4500-5500)
T136479011-18-1
Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. It inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells and is commonly used to model inflammatory bowel disease. The high negative charge from its sulfate groups damages the intestinal mucosal barrier, leading to intestinal barrier dysfunction, macrophage impairment, and bacterial flora disorder.
- $39
Size
QTY
CitedIsoeugenol
4-Propenylguaiacol, 2-Methoxy-4-propenylphenol
T2S049397-54-1
Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
- $29
Size
QTY
L-Ascorbic acid sodium salt
Vitamin C sodium salt, Sodium L-ascorbate, Sodium ascorbate, L-Ascorbic acid sodium, (+)-Sodium L-ascorbate
T6674134-03-2
L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
- $30
Size
QTY
Doxycycline (hyclate) Cited
WC2031, Doxycycline hydrochloride hemiethanolate hemihydrate, Doxycycline hyclate
T1687L24390-14-5
Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor activity.
- $41
Size
QTY
CitedSelect Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. |
| In vitro | Oenothein B (15-45 µM; 24 hours) increased intracellular reactive oxygen species (ROS) and upregulated apoptotic triggers (cleavage caspase-3, PARP, cytosolic cytochrome c, Bax). Oenothein B (15-45 µM) demonstrated a dose- and time-dependent inhibition on A549 cells over 12-72 hours, inhibiting their proliferation by inducing apoptosis and arresting cells at the G1 stage[3]. |
| In vivo | In ICR mice, Oenothein B (100-300 mg/kg; p.o.) reduced neuroinflammation in the brain during systemic inflammation[2]. |
| Molecular Weight | 1569.08 |
| Formula | C68H48O44 |
| Cas No. | 104987-36-2 |
| Smiles | OC1=C(C(C(O)=C2O)=C(C=C2O)C3=O)C(C(O[C@H]4[C@H](OC(C5=CC(O)=C(O)C(O)=C5)=O)[C@@H](OC(C(C=C6O)=C(C(O)=C6O)OC7=C(O)C(O)=C8C9=C7)=O)[C@H](O)O[C@@H]4CO3)=O)=CC(OC(C(O)=C%10O)=C(C=C%10O)C(O[C@@H]%11[C@@H](OC(C%12=CC(O)=C(O)C(O)=C%12)=O)[C@H](OC(C%13=C8C(O)=C(O)C(O)=C%13)=O)[C@@H](COC9=O)O[C@H]%11O)=O)=C1O |
| Relative Density. | 2.20 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Oenothein B | purchase Oenothein B | Oenothein B cost | order Oenothein B | Oenothein B chemical structure | Oenothein B in vivo | Oenothein B in vitro | Oenothein B formula | Oenothein B molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.