Shopping Cart
- Remove All
Your shopping cart is currently empty
Tallimustine HCl
🥰Excellent
Catalog No. T68151LCas No. 118438-45-2
Alias Tallimustine HCl(115308-98-0 Free base)
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
Tallimustine HCl
🥰Excellent
Purity: 98.52%
Catalog No. T68151LAlias Tallimustine HCl(115308-98-0 Free base)Cas No. 118438-45-2
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $430 | In Stock | |
| 10 mg | $636 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,360 | In Stock | |
| 100 mg | $1,830 | In Stock | |
| 500 mg | $3,680 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Tallimustine HCl"
Crystal Violet
Cited
Methyl Violet 10B, Hexamethylpararosaniline chloride, Gentian Violet, Basic Violet 3
T1343L548-62-9
Crystal Violet (Hexamethylpararosaniline chloride) is a triarylmethane dye that is a mixture of violet rosanilinis, with antibacterial, antifungal, and anthelmintic properties.
- $46
Size
QTY
CitedMethoxsalen
Xanthotoxin, NCI-C55903, 8-MOP, 8-Methoxypsoralen
T1548298-81-7
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.
- $29
Size
QTY
Cyclophosphamide Cited
T0707L50-18-0
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
- $35
Size
QTY
CitedCyclophosphamide hydrate Cited
Cyclophosphamide monohydrate
T07076055-19-2
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
- $33
Size
QTY
CitedNorharmane
β-Carboline, 2-Azacarbazole, 2,9-Diazafluorene
T4024244-63-3
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
- $30
Size
QTY
Elinafide
T68061162706-37-8In house
Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.
- $44
Size
QTY
Hydroxychloroquine sulfate Cited
HCQ sulfate, Acidum iopanoicum
T0951747-36-4
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa.
- $48
Size
QTY
CitedQuinacrine dihydrochloride Cited
SN-390, Quinacrine 2HCl, Mepacrine dihydrochloride
T094269-05-6
Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
- $41
Size
QTY
CitedProflavine Hemisulfate
Proflavin hemisulfate, 3,6-Diaminoacridine hemisulfate
T04381811-28-5
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and antiseptic purposes.
- $33
Size
QTY
Chromium picolinate Cited
T457514639-25-9
Chromium picolinate causes DNA damage and mutation. It is an activator of p38.
- $41
Size
QTY
CitedAOH1996
T775202089314-64-5In house
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC). It interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis. AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II, and acts synergistically with DNA damaging agents to inhibit tumor cell growth.
- $60
Size
QTY
Select Batch
Purity:98.52%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia. |
| Targets&IC50 | CEM cells:3.5 nM |
| In vitro | Tallimustine HCl (0.1-10 μM; 4 h) causes harm to isolated SV40 DNA. Additionally, Tallimustine HCl exhibits cytotoxicity in CEM cells after 72 hours, displaying an IC50 of 3.5 nM.[1] Tallimustine HCl (25 and 100 nM, 6 days) induces erythroid differentiation of K562 cells.[2] Tallimustine HCl (100 nM, 6 days) increases accumulation of γ-globin mRNA in K562 cells.[2] Tallimustine HCl (0.5 μg/mL, 1 h) arrests SW626 cells in G2/M phase.[3] |
| In vivo | Tallimustine HCl (3 mg/kg; i.p.; ) prolonged survival and shows antileukemic activity in L1210 tumor-bearing mice and.[4] |
| Alias | Tallimustine HCl(115308-98-0 Free base) |
| Molecular Weight | 734.08 |
| Formula | C32H39Cl3N10O4 |
| Cas No. | 118438-45-2 |
| Smiles | Cl.O=C(NC=1C=C(C(=O)NC=2C=C(C(=O)NC=3C=C(C(=O)NCCC(=N)N)N(C3)C)N(C2)C)N(C1)C)C4=CC=C(C=C4)N(CCCl)CCCl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (61.3 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Tallimustine HCl | purchase Tallimustine HCl | Tallimustine HCl cost | order Tallimustine HCl | Tallimustine HCl chemical structure | Tallimustine HCl in vivo | Tallimustine HCl in vitro | Tallimustine HCl formula | Tallimustine HCl molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.