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Chloroquinoxaline sulfonamide

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Purity:98.67%

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COA HNMR HPLC LCMS

Chloroquinoxaline sulfonamide

Catalog No. T14953Cas No. 97919-22-7

Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.

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Pack Size	Price	Availability
1 mg	$56	In Stock
5 mg	$128	In Stock
10 mg	$187	In Stock
25 mg	$312	In Stock
50 mg	$463	In Stock
100 mg	$678	In Stock
500 mg	$1,430	In Stock
1 mL x 10 mM (in DMSO)	$138	In Stock

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Product Introduction

Bioactivity

Description	Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.
Targets&IC50	CV-1 cells:1.8 mM
In vitro	Chloroquinoxaline sulfonamide-induced protein-DNA cross-links and topoisomerase II-DNA cross-links in CV-1 cells [1]. Chloroquinoxaline sulfonamide inhibits the proliferation of mouse B16 melanoma cells, but only when a relatively high drug concentration (1 mM) is used [2]. The IC50 value of chloroquinoxaline sulfonamide on CV-1 cells was 1.8 mM using MTT cytotoxicity assay.
Alias	NSC-339004, Chloroquinoxaline

Chemical Properties

Molecular Weight	334.78
Formula	C14H11ClN4O2S
Cas No.	97919-22-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (298.70 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9870 mL	14.9352 mL	29.8704 mL	149.3518 mL
5 mM	0.5974 mL	2.9870 mL	5.9741 mL	29.8704 mL
10 mM	0.2987 mL	1.4935 mL	2.9870 mL	14.9352 mL
20 mM	0.1494 mL	0.7468 mL	1.4935 mL	7.4676 mL
50 mM	0.0597 mL	0.2987 mL	0.5974 mL	2.9870 mL
100 mM	0.0299 mL	0.1494 mL	0.2987 mL	1.4935 mL

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