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Chloroquinoxaline sulfonamide
🥰Excellent
Catalog No. T14953Cas No. 97919-22-7
Alias NSC-339004, Chloroquinoxaline
Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.
Chloroquinoxaline sulfonamide
🥰Excellent
Purity: 100%
Catalog No. T14953Alias NSC-339004, ChloroquinoxalineCas No. 97919-22-7
Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $56 | In Stock | |
| 5 mg | $128 | In Stock | |
| 10 mg | $187 | In Stock | |
| 25 mg | $312 | In Stock | |
| 50 mg | $463 | In Stock | |
| 100 mg | $678 | In Stock | |
| 500 mg | $1,430 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $138 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer. |
| Targets&IC50 | CV-1 cells:1.8 mM |
| In vitro | Chloroquinoxaline sulfonamide-induced protein-DNA cross-links and topoisomerase II-DNA cross-links in CV-1 cells [1]. Chloroquinoxaline sulfonamide inhibits the proliferation of mouse B16 melanoma cells, but only when a relatively high drug concentration (1 mM) is used [2]. The IC50 value of chloroquinoxaline sulfonamide on CV-1 cells was 1.8 mM using MTT cytotoxicity assay. |
| Alias | NSC-339004, Chloroquinoxaline |
| Molecular Weight | 334.78 |
| Formula | C14H11ClN4O2S |
| Cas No. | 97919-22-7 |
| Smiles | Nc1ccc(cc1)S(=O)(=O)Nc1cnc2c(Cl)cccc2n1 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (298.70 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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