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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $74 | In Stock | |
5 mg | $178 | In Stock | |
10 mg | $289 | In Stock | |
25 mg | $528 | In Stock | |
50 mg | $769 | In Stock | |
100 mg | $1,080 | In Stock | |
1 mL x 10 mM (in DMSO) | $218 | In Stock |
Description | APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity. |
In vitro | APS6-45 (1 μM; 1 h) strongly inhibits RAS pathway activity signaling in human MTC cell lines TT and MZ-CRC-1[1]. |
In vivo | APS6-45 did not affect body weight of dosed(10 mg/kg) mice after 30 d.APS6-45 (0.1-160 mg/kg; a single p.o.) does not cause detectable toxic effects in mice[1]. |
Molecular Weight | 548.39 |
Formula | C23H16F8N4O3 |
Cas No. | 2188236-41-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 240mg/mL (437.67mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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