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SM360320

Catalog No. T19675Cas No. 226907-52-4
Alias SM-360320, SM 360320, CL-087, CL087, CL 087, 1V136

SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for research on acting as an immunological adjuv

SM360320

SM360320

Purity: 98.4%
Catalog No. T19675Alias SM-360320, SM 360320, CL-087, CL087, CL 087, 1V136Cas No. 226907-52-4
SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for research on acting as an immunological adjuv
Pack SizePriceAvailabilityQuantity
1 mg$118In Stock
5 mg$256In Stock
10 mg$383In Stock
25 mg$592In Stock
50 mg$822In Stock
100 mg$1,090In Stock
500 mg$2,210In Stock
1 mL x 10 mM (in DMSO)$283In Stock
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Purity:98.4%
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Product Introduction

Bioactivity
Description
SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for research on acting as an immunological adjuv
AliasSM-360320, SM 360320, CL-087, CL087, CL 087, 1V136
Chemical Properties
Molecular Weight315.33
FormulaC15H17N5O3
Cas No.226907-52-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (380.55 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1713 mL15.8564 mL31.7128 mL158.5640 mL
5 mM0.6343 mL3.1713 mL6.3426 mL31.7128 mL
10 mM0.3171 mL1.5856 mL3.1713 mL15.8564 mL
20 mM0.1586 mL0.7928 mL1.5856 mL7.9282 mL
50 mM0.0634 mL0.3171 mL0.6343 mL3.1713 mL
100 mM0.0317 mL0.1586 mL0.3171 mL1.5856 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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