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Results for "
antitumor effect
" in TargetMol Product Catalog- Inhibitors & Agonists56
- Compound Libraries3
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- Natural Products18
Trastuzumab deruxtecan
DS-8201a,VRN-101099,DS 8201,T-DXd
T366461826843-81-5
Trastuzumab deruxtecan (T-DXd) is an antibody-active molecule conjugate (ADC) with anticancer and antitumor activity, which is composed of a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2) coupled to a topoisomerase I inhibitor (DXd). Trastuzumab deruxtecan has an improved effect on the treatment of HER2-positive breast cancer and gastric cancer.
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Isatuximab
Isatuximab（anti-CD38）,SAR-650984,hu38SB19,Isatuximab-irfc
T389511461640-62-9
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system, a highly expressed protein in multiple myeloma. It exhibits antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, directly inducing apoptosis without crosslinking. Isatuximab inhibits CD38 extracellular enzyme activity, affecting various cellular functions.
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