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Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $50 | In Stock | |
200 mg | $79 | In Stock | |
500 mg | $158 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. |
In vitro | In diabetic nephropathy-afflicted db/db mice, Rhein effectively ameliorates diabetic renal lesions and mitigates hyperlipidemia by reducing plasma cholesterol (Chol), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), ApoE, and renal tissue transforming growth factor-β1 (TGF-β1). |
In vivo | In chondrocytes, Rhein (35 µM) effectively inhibits the synthesis of IL-1β in human osteoarthritis synovium and exerts effects in cartilage by reducing the amount of IL-1R and inhibiting the production of NO induced by IL-1β. Additionally, Rhein is capable of inducing apoptosis in acute promyelocytic leukemia cells (HL-60). |
Alias | Rhubarb yellow, Rheinic Acid, Rheic Acid, NSC 38629, Monorhein |
Molecular Weight | 284.22 |
Formula | C15H8O6 |
Cas No. | 478-43-3 |
Smiles | OC(=O)C1=CC2=C(C(O)=C1)C(=O)C1=C(C=CC=C1O)C2=O |
Relative Density. | 1.3269 g/cm3 (Estimated) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 5.45 mg/mL (19.19 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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