Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
2 mg | In stock | $ 297.00 | |
5 mg | In stock | $ 455.00 | |
10 mg | In stock | $ 672.00 | |
25 mg | In stock | $ 1,060.00 | |
50 mg | In stock | $ 1,430.00 | |
100 mg | In stock | $ 1,920.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 573.00 |
Description | LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively). |
Targets&IC50 | LDHA:32 nM (IC50), LDHB:27 nM (IC50) |
In vitro | LDH-IN-1 exhibit low nM inhibition of both LDHA and LDHB, submicromolar inhibition of lactate production, and inhibition of glycolysis in MiaPaCa2 pancreatic cancer and A673 sarcoma cells. |
In vivo | LDH-IN-1 shows clearance values that far exceed hepatic blood flow ?in mouse species (90 mL/min/kg), with in vivo clearances of 227 mL/min/kg[1]. |
Molecular Weight | 570.68 |
Formula | C30H26N4O4S2 |
CAS No. | 1964515-43-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (87.61 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LDH-IN-1 1964515-43-2 Metabolism Dehydrogenase Lactate Dehydrogenase inhibit LDH LDH IN 1 Inhibitor LDHIN1 inhibitor