Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 213.00 | |
10 mg | In stock | $ 313.00 | |
25 mg | In stock | $ 533.00 | |
50 mg | In stock | $ 768.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 213.00 |
Description | LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). |
Targets&IC50 | PLA2G16:20 nM(Ki) |
In vitro | LEI110 reduces cellular arachidonic acid levels in PLA2G16-overexpressing U2OS cells and oleic acid-induced steatosis in human HepG2 cells[1]. |
Molecular Weight | 456.46 |
Formula | C25H23F3N2O3 |
CAS No. | 2313525-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (109.54 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LEI110 2313525-90-3 Metabolism Phospholipase HepG2 cells inhibit thiol hydrolases LEI-110 Inhibitor lipolysis LEI 110 inhibitor