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Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $36 | In Stock | |
100 mg | $50 | In Stock | |
200 mg | $71 | In Stock | |
500 mg | $119 | In Stock |
Description | Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity. |
In vitro | Triiodothyronine (0.01-0.1 μM) results in a decrease in the TRalpha1:TRalpha2 mRNA ratio in HepG2 cells. High liothyronine levels induces a low TRalpha1:TRalpha2 ratio which can protect the cell from excessive triiodothyronine-induced gene expression[1]. |
Alias | Triiodothyronine, Tresitope, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Lyothyronine, L-3,3',5-Triiodothyronine, 3,3',5-Triiodo-L-thyronine |
Molecular Weight | 650.97 |
Formula | C15H12I3NO4 |
Cas No. | 6893-02-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4.95 mg/mL (7.6 mM), Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. DMSO: 1 mg/mL, Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
10% DMSO+40% PEG300+5% Tween 80+45% Saline
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