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MST-312

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Catalog No. T41290Cas No. 368449-04-1
Alias Telomerase Inhibitor IX

MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).

MST-312

MST-312

🥰Excellent
Purity: 99.17%
Catalog No. T41290Alias Telomerase Inhibitor IXCas No. 368449-04-1
MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$44In Stock
10 mg$73In Stock
25 mg$147In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.17%
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Product Introduction

Bioactivity
Description
MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
In vitro
In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].
AliasTelomerase Inhibitor IX
Chemical Properties
Molecular Weight380.35
FormulaC20H16N2O6
Cas No.368449-04-1
SmilesOc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O
Relative Density.1.578 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Insoluble
DMSO: 50 mg/mL (131.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6292 mL13.1458 mL26.2916 mL131.4579 mL
5 mM0.5258 mL2.6292 mL5.2583 mL26.2916 mL
10 mM0.2629 mL1.3146 mL2.6292 mL13.1458 mL
20 mM0.1315 mL0.6573 mL1.3146 mL6.5729 mL
50 mM0.0526 mL0.2629 mL0.5258 mL2.6292 mL
100 mM0.0263 mL0.1315 mL0.2629 mL1.3146 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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