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MST-312

Catalog No. T41290 CAS 368449-04-1

Synonyms: Telomerase Inhibitor IX

MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

MST-312, CAS 368449-04-1

Pack Size	Availability	Price/USD
2 mg	In stock	$ 34.00
5 mg	In stock	$ 55.00
10 mg	In stock	$ 97.00
25 mg	In stock	$ 197.00
50 mg	In stock	$ 367.00
100 mg	In stock	$ 546.00
1 mL * 10 mM (in DMSO)	In stock	$ 61.00

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Purity: 99.17%

Purity: 98.87%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
In vitro	In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].

Synonyms	Telomerase Inhibitor IX
Molecular Weight	380.35
Formula	C20H16N2O6
CAS No.	368449-04-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 70 mg/mL (184.04 mM), Sonification and heating to 60℃ are recommended.

References and Literature

1. Ameri Z, et al. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes. Life Sci. 2019;228:66-71.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Inhibitor Library Bioactive Compound Library DNA Damage & Repair Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MST-312 368449-04-1 DNA Damage/DNA Repair Telomerase EGCG epigallocatechin gallate MST312 Inhibitor multiple tea MST 312 derivative cancer inhibit Telomerase Inhibitor IX myeloma inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.