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N-Desmethyl-Apalutamide

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Catalog No. T12146Cas No. 1332391-11-3
Alias N-Desmethyl Apalutamide

N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.

N-Desmethyl-Apalutamide

N-Desmethyl-Apalutamide

🥰Excellent
Purity: 97.83%
Catalog No. T12146Alias N-Desmethyl ApalutamideCas No. 1332391-11-3
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
Pack SizePriceAvailabilityQuantity
1 mg$119In Stock
5 mg$273In Stock
10 mg$393In Stock
25 mg$592In Stock
50 mg$816In Stock
100 mg$1,090In Stock
200 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$293In Stock
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Purity:97.83%
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Product Introduction

Bioactivity
Description
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.
AliasN-Desmethyl Apalutamide
Chemical Properties
Molecular Weight463.41
FormulaC20H13F4N5O2S
Cas No.1332391-11-3
SmilesNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C11CCC1)c1cnc(C#N)c(c1)C(F)(F)F
Relative Density.1.65 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (107.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1579 mL10.7896 mL21.5792 mL107.8958 mL
5 mM0.4316 mL2.1579 mL4.3158 mL21.5792 mL
10 mM0.2158 mL1.0790 mL2.1579 mL10.7896 mL
20 mM0.1079 mL0.5395 mL1.0790 mL5.3948 mL
50 mM0.0432 mL0.2158 mL0.4316 mL2.1579 mL
100 mM0.0216 mL0.1079 mL0.2158 mL1.0790 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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