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Naftopidil hydrochloride
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Purity:99.95%
Naftopidil hydrochloride
Catalog No. T9220Cas No. 1164469-60-6
Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respectively. Naftopidil hydrochloride has antiproliferative effects.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $61 | In Stock | |
| 2 mg | $87 | In Stock | |
| 5 mg | $131 | In Stock | |
| 10 mg | $198 | In Stock | |
| 25 mg | $356 | In Stock | |
| 50 mg | $533 | In Stock | |
| 100 mg | $769 | In Stock | |
| 500 mg | $1,580 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $163 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respectively. Naftopidil hydrochloride has antiproliferative effects. |
| In vitro | Naftopidil hydrochloride reduced the extent of lung fibrosis and SP‐D production in bleomycin‐induced lung fibrosis in mice[1]. |
| In vivo | Naftopidil hydrochloride strongly suppressed cell proliferation of stromal cells, resulting in decreased tumorigenic soluble factor, suggesting that naftopidil might be effective in preventing stromal support of tumor cells[2]. |
| Alias | 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-, KT-611 hydrochloride, BM-15275 hydrochloride |
| Molecular Weight | 428.95 |
| Formula | C24H29ClN2O3 |
| Cas No. | 1164469-60-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/ml (139.88 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Keywords
BM-15275BM15275canineprostaticKT611 HydrochlorideNaftopidilprostateKT-611 HydrochloridehyperplasiainhibitBM-15275 HydrochlorideKT 611 HydrochlorideInhibitorNaftopidil hydrochlorideKT-611Adrenergic ReceptorBM 15275 HydrochlorideKT611Naftopidil HydrochlorideKT 611pressureBM15275 HydrochlorideBM 15275Beta Receptor
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